SS-31
SS-31 (elamipretide) is a mitochondria-targeting peptide. It received FDA accelerated approval for Barth syndrome, a rare genetic disease. Research-grade SS-31 is not that product.
What it is
A small peptide that binds to a lipid in the inner mitochondrial membrane.
What the evidence shows
In people
Trials in rare mitochondrial diseases have shown mixed results. Evidence for general anti-aging use does not exist.
In animals and labs
Animal studies suggest benefits for mitochondrial function in aging models.
Legal status
Approved only for Barth syndrome under accelerated approval.
Dosing
Only the approved product has a defined dose
The approved product has a dose on its FDA label for one specific use. That dose does not apply to research-grade versions, which can differ in strength and purity. Talk to a prescriber about the approved product.
Known risks
- Injection-site reactions
- Unknown effects in healthy people