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Educational summary · not yet reviewed by a medical professional

EARLYSupplement or cosmetic·Not on the WADA list

Glutathione

Also called L-glutathione, GSH

Glutathione is a natural antioxidant tripeptide sold as an oral supplement. Evidence for health or skin benefits is limited, and IV or injectable glutathione is not an approved product.

What it is

A three-amino-acid peptide the body makes to neutralize free radicals.

What the evidence shows

In people

Small trials show oral forms can raise blood levels; evidence for clinical benefits is limited.

In animals and labs

Extensive lab research on its antioxidant role.

Legal status

Legal as an oral supplement. Injectable and IV products are not FDA-approved drugs.

Dosing

Follow the product label

Supplements and skincare products are used as directed on their label. Choose products with third-party testing, and check with a clinician if you are pregnant, nursing, or take medication.

Known risks

  • Generally well tolerated orally
  • IV use carries infection and contamination risk

Sources

Last updated 2026-11-03

Educational only and not medical advice. Talk to a licensed clinician before starting any peptide. Medical disclaimer.