Argireline
Argireline is a skincare peptide used to soften the look of expression lines. Small studies show modest effects, much weaker than injectable treatments.
What it is
A six-amino-acid peptide that may reduce muscle-contraction signals in the skin.
What the evidence shows
In people
Small studies report modest reductions in the depth of expression lines.
In animals and labs
Lab studies on nerve-muscle signaling.
Legal status
Legal as a cosmetic ingredient.
Dosing
Follow the product label
Supplements and skincare products are used as directed on their label. Choose products with third-party testing, and check with a clinician if you are pregnant, nursing, or take medication.
Known risks
- Mild irritation in sensitive skin