
Creatine monohydrate: benefits, timing, loading, side effects, and what the evidence says
Creatine monohydrate has strong evidence for strength, power, and repeated high-intensity exercise. Research has not established a clear before-versus-after workout timing advantage, a loading phase is optional rather than required, large trial analyses do not show an overall side-effect increase versus placebo, and a 2025 randomized trial found no hair-loss signal over 12 weeks in resistance-trained men.
