Semax
Semax is a synthetic peptide approved in Russia, mainly for stroke recovery and cognitive conditions. It is not FDA-approved, and most studies are small and from Russian groups.
What it is
A peptide based on a fragment of the hormone ACTH, given as a nasal spray.
What the evidence shows
In people
Small clinical studies, mostly in Russian populations, report neurological benefits.
In animals and labs
Animal studies on brain-derived neurotrophic factor and nerve protection.
Legal status
Not FDA-approved.
Dosing
There is no established human dose
No regulator has approved a dose for human use. Numbers shared online come from animal studies, small early trials, or seller protocols, and none of them have been shown to be safe or effective. BOTH does not publish dosing, mixing, or injection instructions for unapproved compounds.
Known risks
- Limited independent safety data
- Possible effects on the stress hormone system
Read our in-depth article on Semax →